SFI 2013

Welcome coffee

Salon AdenauerPEPROTECH
PLENARY SESSION: Lymphocyte Migration

Chairs: Ana-Maria Lennon (Paris) and Philippe Bousso (Paris)

Reinhold Förster (Hannover, Germany): Lymph node homing of immune cells via afferent lymphatics

Jens Stein (Bern, Switzerland): In situ visualization of naïve, central and effector memory T cell migration and activation

Emmanuel Donnadieu (Paris, France): T cell migration in tumors: a role for matrix architecture

Milka Sarris (Paris, France): Neutrophil guidance and gradient sensing in vivo: lessons from zebrafish

Salon Honnorat & Galeries Coffee break - Visit of exhibition - Poster session

PARALLEL WORKSHOPS

Salon AdenauerImmune Signaling

Chairs: Claire Hivroz (Paris) and Didier Marguet (Marseille)

Claire Hivroz: Investigating mechanotransduction in T cell

Didier Marguet: Seeing is believing

Selected short oral presentations

Joël Babdor (Paris, France): Storage endosomes control TLR9 signaling in dendritic cells

Jean-Marie Carpier (Paris, France): VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites

Jérôme Delon (Paris, France): Fam65b is a new transcriptional target of FOXO1 that regulates RhoA signaling for T lymphocyte migration

Yannick Hamon (Marseille, France): Essential role for raft nanodomains in initiation of T cell receptor signalling upon antigen recognition

Hélène Moreau (Paris, France): Regulation and signaling properties of T cell immunological synapses and kinapses in vivo

Salon GulbenkianNeuroimmunology

Chairs: Roland Liblau (Toulouse) and Sylvain Fisson (Paris)

Roland Liblau: T cell targeting of CNS neurons

Sylvain Fisson: Immune sanctuaries as a rosetta stone for systemic non Hodgkin B cell lymphomas?

Selected short oral presentations

Cira Dansokho (Paris, France): Depletion of regulatory T cells modulates disease progression and signature in a murine model of Alzheimer’s disease

Sarantis Korniotis (Paris, France): Innate pro-B cell progenitors protect against ongoing experimental autoimmune encephalomyelitis by restraining T-cell homing to the central nervous system

Lennart Mars (Toulouse, France): Myelin-specific T cells that co-recognise a neuronal autoantigen drive chronic Experimental Autoimmune Encephalomyelitis

Charlotte Pouchy (Paris, France): Control of central nervous system inflammation by regulatory T cells depends on TNF/TNFR2

Salon David-WeillImmunological memory

Chairs: Jacqueline Marvel (Lyon) and Claude-Agnès Reynaud (Paris)

Jacqueline Marvel: A new gene-expression signature associated with protective memory CD8 responses

Claude-Agnès Reynaud: Multiple players in B cell memory

Selected short oral presentations

Assia Asrir (Toulouse, France): In vivo caracterisation of memory T follicular helper subpopulation

Florent Carrette (La Jolla, USA): Hyaluronic acid/CD44 interactions control CD8 T cell memory development to influenza virus infection

Morgan Grau (Lyon, France): CCL5 and NKG2D expression is restricted to antigen-induced memory CD8 T cells

Roxana Khazen (Toulouse, France): Dissecting early mechanisms of melanoma cell resistance to cytotoxic T lymphocyte attack

Simon Le Gallou (Paris, France): AID dependent memory response in unimmunized mice

Maison de la BelgiqueLunch

Maison InternationaleVisit of exhibition - Poster session

Salon AdenauerPLENARY SESSION: Mucosal Immunity
with the Japanese Society for Immunology

Chairs: Gérard Eberl (Paris) and Hiroshi Kiyono (Tokyo)

Hiroshi Kiyono (Tokyo, Japan): Reverse Control of ATP-P2X7-dependent Mast Cells in Mucosa and Skin for Inflammation

Satoshi Uematsu (Tokyo, Japan): Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

Noriko Tsuji (Ibaraki, Japan): Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers TLR3-mediated production of protective IFN-β

Bart Lambrecht (Ghent, Belgium): The lung dendritic cell network and the response to allergens

Fiona Powrie (Oxford, UK): IL-23-driven cellular and molecular pathways that promote intestinal inflammation and colon cancer

Salon Honnorat & GaleriesCoffee break - Visit of exhibition - Poster session

PARALLEL WORKSHOPS

Salon AdenauerFMC session: Progress in Autoimmunity

Chairs: Catherine Johanet (Paris) and Alain Chevailler (Angers)

Yves Renaudineau (Brest): Epigenetics and autoimmunity: Epigénétique et autoimmunité

Céline Beauvillain (Angers): NETose et autoimmunité: NETosis and autoimmunity

Catherine Johanet: Antiphospholipase A2 Receptor (anti PLI2R) antibodies: Anticorps anti-récepteur à la phospholipase A2 (anti PLI2R)

Nicole Fabien (Pierre-Bénite): New antibodies in auto-immune myopathies: Les nouveaux autoanticorps dans les myopathies auto-immunes

Salon GulbenkianInnate Lymphoid Cells

Chairs: James Di Santo (Paris) and Sophie Ugolini (Marseille)

James Di Santo: IL-22-Producing Innate Lymphoid Cells: Mediators of Immune Defense and Regulators of Tissue Homeostasis

Sophie Ugolini: Natural Killer cells, Innate Lymphoid cells and Innate Immunity

Selected short oral presentations

Sophie Caillat Zucman (Paris, France): Development and maturation of MAIT cells in human neonates : relations with gestational age and microbial infection

Julie Déchanet-Merville (Bordeaux, France): Sensing cellular stress by human Gamma-Delta TCR

Nicolas Serafini (Paris, France): The transcription factor GATA-3 drives development of innate lymphoid cells

Karine Serre (Lisboa, Portugal): In vivo molecular signatures of stable versus plastic gamma delta T cell subset

Salon David-WeillAllergy & Asthma

Chairs: Valérie Julia (Valbonne) and Maria Leite-de-Moraes (Paris)

Valérie Julia: Blocking allergen-specific T cell maintenance in inflamed tissues: a possible therapeutic strategy to treat allergic diseases?

Maria Leite-de-Moraes: Invariant Natural Killer T cells from Biology to Pathology: Focus on Allergic Asthma

Selected short oral presentations

Uta Baddack (Toulouse, France): The onset of inflammation dictates the timing for the initiation of T cell immunity against Mycobacterium tuberculosis

Héloïse Beutier (Paris, France): Relative contribution of IgG receptors in IgG1 and IgG2b-dependent anaphylactic reactions

Angèle Cortial (Lyon, France): New vectors for the immunobiological diagnosis of contact allergy to fragrances

Marie-Caroline Dieu-Nosjean (Paris, France): Tertiary lymphoid structure dendritic cells signal a Th1 and cytotoxic immune contexture, and are required for good prognostic value of CD8+ T cells in lung cancer patients

Salon GulbenkianSFI General Assembly

MILTENYI BIOTEC
Gala evening: dinner cruise on the River Seine