EAVPT 2015

PARALLEL SESSIONS

Antiparasitics internal & external

Rooms G-H

Chairs: C. Lanusse and D. Larsen

Pharmacology-based strategies to optimize drug activity against resistant helminth parasites in ruminants
Carlos Lanusse - Tandil (AR)

An overview of the Pharmacokinetics of an Isoxazoline: a New Class of Parasiticide for Dogs
Diane Larsen - North Brunswick (US)

Short oral communications

Evaluation of the tolerance of a permethrin-dinotefuran-pyriproxyfen combination (Vectra^®3D) after topically repeated overdosed administration in young puppies
E. Coussanes - Libourne (FR)

ABCG2-mediated transport of anthelmintic drugs in the mammary gland of dairy cows
S. Halwachs - Leipzig (GE)

On the mode of action of emodepside and diethylcarbamazine
R. J. Martin - Ames (US)

Not just GluCls (Glutamate-gated Chloride channels): Abamectin has potent effects on nicotinic acetylcholine receptors of nematode parasites
R. J. Martin - Ames (US)

Pharmacokinetics 2

Auditorium 450

Chairs: M. Martinez and J. Mochel

Use of in silico models to support drug and drug product understanding
Marilyn Martinez - Rockville (US)

Short oral communications

Pharmacokinetics of the angiotensin receptor-neprilysin inhibitor LCZ696 in furosemide-treated dogs
J. Mochel - Basel (SZ)

Simultaneous intravenous and subcutaneous population modelling of robenacoxib disposition kinetics in cats
L. Pelligand - Hatfield (UK)

Preliminary results of potential lateral distribution of permethrin over horse skin
A. Werners - St. George (GD)

Drug transporters & biotransformation 1

Room 200

Chairs: M. Dacasto and K. Mealey

Pharmacogenetics Of Cytochromes P450 In Veterinary Species: An Update
Mauro Dacasto - Legnaro (IT)

Short oral communications

Comparative study on the expression and activity of hepatic enzymes responsible for dioxin-like compound biotransformation in sheep and cows
F. Girolami - Grugliasco (IT)

Interaction of the bovine mammary ABCG2 efflux transporter with AFB1 and the modulation of its activity by PCB126
L. Manzini - Grugliasco (IT)

The ontogeny of hepatic CYP3A, CYP2C and CYP2E enzyme activity in conventional pigs
J. Millecam - Merelbeke (BE)

Correlation between Dextromethorphan and Debrisoquine metabolism and CYP2D50 genotype in Thoroughbred horses
H. Knych - Davis (US)

Antimicrobials 3 & Antibiograms

Rooms G-H

Chairs: D. Mevius and A. Bousquet-Melou

The consequences of generic marketing on antibiotic consumption and the spread of antimicrobial resistance: the need for new antibiotics
Alain Bousquet-Melou - Toulouse (FR)

Veterinary Committee on Antimicrobial Susceptibility Testing (VetCAST)
Dik Mevius - Lelystad (NL)

Short oral communications

The revised draft of the EMA/CVMP ‘Guideline for the demonstration of efficacy for VMPs containing antimicrobial substances’: Requirements to field studies
K. Hellmann - Munich (GE)

Regulation and guidelines of veterinary antimicrobial therapy and animal welfare in the Netherlands - from a small animal perspective
L. Schipper - Utrecht (NL)

Zoonotic disease control: collaboration to control infectious diseases affecting multiple species
L. Reeve-Johnson - Brisbane (AS)

Drug transporters & biotransformation 2

Room 200

Chairs: M. Dacasto and K. Mealey

Clinical relevance of ABC transporter polymorphisms in the dog and cat
Katrina Mealey - Pullman (US)

Short oral communications

Use of liver slices to assess metabolic drug-drug interactions in cattle
G. Virkel - Tandil (AR)

Transcriptomic characterization of Marby Darby Bovine Kidney (MDBK) cell line and its comparison with cattle primary hepatocytes and liver tissue
R. Elgendy - Legnaro (IT)

Regulation Of Bovine CYP3A28 Promoter By Pregnane X Receptor (PXR) And Constitutive Androstane Receptor (CAR)
M. Giantin - Legnaro (IT)

Bovine liver slices as a model to evaluate metabolic interactions between flukicidal (triclabendazole) and nematodicidal (oxfendazole, fenbendazole) molecules
P. Viviani - Tandil (AR)

Exonic Polymorphisms Of Cytochrome P450 3As (CYP3As) In Piedmontese Cattle Breed
M. Giantin - Legnaro (IT)

Pharmacodynamics 2 - Pain/Inflammation

Auditorium 450

Chairs: J.-C. Desfontis and B. Ranheim

Quantification of pain and nociception in inflammation models
Olivier Levionnois - Bern (SZ)

Pain models in domestic animals
Birgit Ranheim - Oslo (NO)

Short oral communications

Synergistic interaction between tapentadol and flupirtine in the rat orofacial formalin test
H.-K. Lee - Daejeon (KS)

Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Anti-Pruritic and Anti-Inflammatory Responses in a Mouse Model of Allergic Dermatitis
T. Fukuyama - Raleigh (US)

Hepatic microsomal stability of human CYP2C9 substrates between marsupials and the rat: a preliminary study
M. Govendir - Sydney (AS)

Evaluation of the anti-inflammatory properties of ketoprofen in bovine and porcine in vivo models using a HPLC-MS/MS multi-method
P. De Backer - Merelbeke (BE)

Local tolerance assessment of two Ketoprofen based solutions for injection at 15 and 10% administered by intramuscular route in swine
M. Salichs - Barcelona (ES)

Evidence-based veterinary medicine & Innovative learning

Room 200

Chairs: L. Schipper and V. Fajt

How best to integrate EBVM into veterinary curricula
Virginia Fajt - College Station (US)

Veterinary pharmacologists’ responsibilities in supporting the practice of evidence-based veterinary medicine
Virginia Fajt - College Station (US)

Developing a virtual learning environment for veterinary pharmacology and toxicology
Jérôme Del Castillo - Saint-Hyacinthe (CA)

Toxicology 2 - Clinical/small animals

Rooms G-H

Chairs: J. N. Edwards and H. Pouliquen

New trends in poisoning treatment - lipidotherapy
John Nick Edwards - London (UK)

Short oral communications

Acute hepatotoxicity of nano- and micro-sized iron particles in adult albino rats
G. Hasabo - Cairo (EG)

Presumptive mycotoxicosis in dog after eating mouldy walnuts
M. Kammerer - Nantes (FR)

Non-convulsive status epilepticus– translational research cases: humans and dogs
L. Reeve-Johnson - Brisbane (AS)