SFI 2016

Espaces S1/S2Welcome coffee

German Society for Immunology (DGfI): Biology of B cells  

Salle Louis Armand Ouest

Chair: Marta Rizzi - Universitäts Klinikum Freiburg - Freiburg (DE)

• Andreas Radbruch - German Rheumatology Research Center - Berlin (DE): Memory plasma cells and memory B cells
• Klaus Rajewsky - Max Delbrück Center for Molecular Medicine - Berlin (DE): A mouse model of Epstein-Barr-Virus infection
• Kathrin Pieper - Institute for Research in Biomedicine - Bellinzona (CH): A new mechanism of immunoglobulin diversification generates broadly reactive antibodies to Plasmodium falciparum
• Jürgen Wienands - Georg August University of Göttingen (DE): Primary and secondary B cell activation

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Checkpoint inhibitors against cancer

Amphi. Gaston Berger

Chairs: Antoine Toubert - Institut Universitaire d'Hématologie, Inserm, Université Paris VII-USPC - Paris (FR) and Eric Tartour - Paris Cardiovascular Research Center, Université Paris V-USPC - Paris (FR)

• Laurence Zitvogel - Institut Gustave-Roussy, Inserm, Université Paris XI - Villejuif (FR): Oncobiotics ameliorate immune checkpoint blockade
• Caroline Robert - Institut Gustave-Roussy, Inserm, Université Paris XI - Villejuif (FR): Melanoma, a model for immunotherapy

Selected short oral presentations

• Magalie Dosset - Inserm, EFS, UBFC - Besançon (FR): Immunogenic cell death inducers trigger PD-L1-dependent adaptive immune resistance to cancer
• Laurie Menger - Institut Curie, Inserm - Paris (FR): TALEN-Mediated Inactivation of PD-1 in tumor-reactive lymphocytes promotes intratumoral T-cell persistence and rejection of established tumors
• Sylvain Simon - Inserm - Nantes (FR): Emergence of high avidity Melan-A specific neoclonotypes defined by high PD-1 and TIGIT co-expression in melanoma patients responding to anti-PD1 treatment

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ILC, NKT and MAIT cells

Salle Louis Armand Est

Chairs: Anne Caignard - Institut Universitaire d'Hématologie, Inserm, Université Paris Diderot-USPC - Paris (FR) and Maria Leite-de-Moraes - Institut Necker-Enfants Malades Inserm, CNRS, Université Paris V-USPC - Paris (FR)

• James Di Santo - Institut Pasteur, Inserm - Paris (FR): Transcriptional regulation of innate lymphoid cell differentiation
• Agnès Lehuen - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR): MAIT cells at the crossroad of microbiota, inflammation and diabetes

Selected short oral presentations

• Christelle Harly - National Institute of Health - Bethesda (US): TCF7 coordinates a transcriptional program underlying early innate lymphoid cell development that overlaps with the T cell developmental program
• Nicolas Huot - Institut Pasteur - Paris (FR): Migration of NK cells into B cell follicles during SIVagm infection
• Marie-Laure Michel - Institut Necker-Enfants Malades - Paris (FR): SLAM-associated protein favors the development of iNKT2 over iNKT17 cells

Acteria Alumni Session   

Salle Louis Armand Ouest

Chairs: Anne Hosmalin - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR) and Hans Yssel - Centre d'Immunologie et des Maladies Infectieuses, Inserm, Université Paris VI, Sorbonne Universités - Paris (FR)

• Nicolas Manel - Institut Curie, Inserm - Paris (FR): Interactions of Dendritic Cells with Viruses
• Dietmar Zehn - Technical University of Munich - Freising (DE): T Cell subset diversification in chronic infections
• Chris Schiering - Francis Crick Institute - London (UK): Feedback control of AhR signalling regulates intestinal immunity
• Thomas Marichal - GIGA-Research Institute - Liège (BE): Role of keratinocyte RAB guanine nucleotide exchange factor 1 (RABGEF1) in skin homeostasis
• Alexander Eggel - Institute of Immunology, University of Bern (CH): Therapeutic approaches to interfere with IgE-mediated allergic reactions

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Anti-tumor immunity   

Amphi. Gaston Berger

Chairs: Nathalie Labarrière - Université de Nantes, Inserm, CNRS - Nantes (FR) and Jean-Luc Teillaud - Centre de Recherche des Cordeliers, Inserm, Université Paris V-USPC - Paris (FR)

• Nathalie Bendriss-Vermare - Centre de Recherche en Cancérologie de Lyon, Inserm, CNRS, Université de Lyon (FR): Dual role of plasmacytoid dendritic cells in breast cancer immunity and therapeutic functional reprogramming
• Jérôme Galon - Centre de Recherche des Cordeliers, Inserm, Université Paris V-USPC - Paris (FR): From immune contexture to Immunoscore in the era of cancer immunotherapies
• Éric Vivier - Centre d’Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR): Evidence of innate lymphoid cell redundancy in mice and humans

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B cells

Salle Louis Armand Est

Chairs: Claudine Schiff - Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR) and François Huetz - Institut Pasteur, Inserm - Paris (FR)

• Michel Cogné - CNRS, Université et CHU de Limoges (FR): Dragged with an Ig super-enhancer
• Claude-Agnès Reynaud - Institut Necker Enfants Malades, Inserm, CNRS, Université Paris V-USPC - Paris (FR): A large IgM memory subset in mouse spleen is constantly renewed by persistent clones from Peyer's patches immune responses

Selected short oral presentations

• Nagham Alouche - Inserm - Clamart (FR): CXCR4 desensitization regulates TLR-mediated plasma cell differentiation and persistence
• Florent Arbogast - Institut de Biologie Moléculaire et Cellulaire Strasbourg, CNRS - Strasbourg (FR): Macroautophagy in B cells activation and antigen presentation
• Vincent Gies - Institut de Biologie Moléculaire et Cellulaire Strasbourg, CNRS - Strasbourg (FR): Human thymic B cells have an APC phenotype and express AIRE