Thursday 1 December
Technological Workshop: ‘Immunogene editing’
08:00
Registration
08:25-08:30
Introduction to the workshop
Ignacio Anegon - Inserm 1064-CRTI, Nantes (FR)
08:30-09:00
Improved genome editing efficiency and flexibility using modified oligonucleotides with TALEN and CRISPR-Cas9 nucleases
Jean-Paul Concordet - Museum d’Histoire Naturelle, Paris (FR)
09:00-09:30
Generation of CRISPRs and delivery of gene-specific nucleases
Tuan H. Nguyen - Inserm 1064-CRTI, Nantes (FR)
09:30-09:50
Tools for Successful Genome Editing in Hematopoietic Cells
Irit Paz - Takara Bio Europe, Saint-Germain-en-Laye (FR)
09:50-10:30
Coffee break
10:30-11:00
Using CRISPR/Cas9 to study antigen presentation to unconventional T-cells
Angharad Lloyd - Cardiff University (UK)
11:00-11:30
Dissection of regulatory networks in primary immune cells using a genome-wide CRISPR-Cas9 library
Oren Parnas - Broad Institute, Harvard (US)
11:30-12:00
Genome editing of immune genes in C. elegans
Nathalie Pujol - CIML, Marseille (FR)
12:00-12:30
Exploring the mechanisms of immunoglobulin class switch recombination using CRISPR/Cas9
Bernardo Reina San Martin - IGBMC, Strasbourg (FR)
12:30-14:00
Lunch
14:00-14:30
Genome editing in rats using CRISPRs, ZFNs and TALENs
Ignacio Anegon - Inserm 1064-CRTI, Nantes (FR)
14:30-15:00
Applying gene editing for generating allogeneic CAR T-cells with improved functionalities
Philippe Duchateau - Cellectis, Paris (FR)
15:00-15:30
Coffee break
15:30-16:00
Targeted genome and epigenome editing as a therapeutic approach to treat HIV infection
Claudio Mussolino - University Medical Center Freiburg, Freiburg (GE)
16:00-16:30
Exploiting the CRISPR/Cas9 system to decipher the role of redundant genes in Th17 cells
Cédric Louvet - Inserm 1064, Nantes (FR)
16:30-17:00
Towards gene editing for the treatment of IPEX syndrome
Rosa Bacchetta - Stanford University (US)